Semaglutide injection sites, without the guesswork
Tap where your last shot went and get a simple weekly rotation across the three areas the label lists.
Plan your rotation
Where did your last shot go?
First shot? Choose the spot with your clinician and the Instructions for Use — then come back to plan the rotation.
Which day is shot day?
Pick your last spot and your plan appears here.
Your next eight weeks
A different area every week, alternating sides — so every spot rests for six.
Then the loop starts over. Saved on this device, so your plan is here next week.
What the semaglutide labels actually say
Semaglutide is the active ingredient in Ozempic and Wegovy — both once-weekly injections given subcutaneously, into the fat just under the skin. MedlinePlus, the NIH’s plain-language drug reference, gives three areas for semaglutide injection: the stomach area, the thigh, and the upper arm. The brand Instructions for Use agree, add that abdomen injections stay two inches clear of the belly button, and note that the back of the upper arm needs someone else to do the injecting.
Why rotating matters
Every semaglutide label carries the same second instruction: change the injection site with each dose. The concern is the tissue under the skin. Cleveland Clinic describes lipohypertrophy — fatty lumps that build where injections repeatedly land — and recommends exactly what the label does: rotate sites, and keep one injection about a finger width from the last.
Is there an official rotation order?
No official sequence exists. Rotation is required; the shape of it is yours to decide, and an undecided rotation quietly becomes the same two spots. The loop here is one clean answer: six spots over three areas, one a week, alternating sides, then back to the start. Use it to stay organized — and defer to any pattern your clinician has given you.
Read the full guide: where to inject a GLP-1 →Planners for other medications
Semaglutide injection sites, answered
Where do you inject semaglutide?
MedlinePlus and the brand Instructions for Use both give the stomach area, the thigh, and the upper arm, for a once-weekly injection under the skin. Abdomen injections stay at least two inches from the belly button, and the back of the upper arm is for when another person injects. Which area suits you best is a conversation for your clinician.
Do you have to rotate semaglutide injection sites?
The labels say to change the injection site with each dose rather than reuse one spot. Rotation is generally recommended to protect the skin you inject into.
What is lipohypertrophy?
Cleveland Clinic describes it as a lump of fatty tissue under the skin that can follow repeated injections in the same area. Changing sites each time helps reduce the risk.
Is it the same for Ozempic and Wegovy?
Both are semaglutide and both name the same three areas, so the rotation is the same either way. There are dedicated planners for each, and Tonic tracks whichever you’re on.
Sources
- Semaglutide Injection — MedlinePlus Drug Information — NIH MedlinePlus
- Ozempic (semaglutide) injection — Label & Instructions for Use — FDA / DailyMed
- Lipohypertrophy — Symptoms, Causes, Treatment & Prevention — Cleveland Clinic
On semaglutide? Tonic logs each shot, remembers your rotation, and suggests the next spot when dose day comes around.
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